Object Details
- Genentech, Inc.
- Description (Brief)
- This silver metal canister once contained Eco RI, an enzyme commonly used in molecular biology. Eco RI belongs to a class of enzymes known as restriction enzymes, which are useful for their ability to cleave DNA only at locations containing specific sequences of nucleotides, the small chemical units that make up the longer DNA molecule. Eco RI recognizes the sequence GAATTC and will cut between the G and first A.
- This particular canister of Eco RI was used to create recombinant DNA molecules at Genentech, a biotechnology company, in the early 1980s.
- Source:
- National Library of Medicine Medical Subject Headings. “Deoxyribonuclease EcoRI.” http://www.nlm.nih.gov/cgi/mesh/2011/MB_cgi?mode=&term=Eco-RI
- Location
- Currently not on view
- Credit Line
- Gift of Genentech
- 1985-03
- ID Number
- 2012.0198.27
- accession number
- 2012.0198
- catalog number
- 2012.0198.27
- Object Name
- Eco RI
- Physical Description
- solution in potassium phosphate, 10 mmol/l (overall active ingredients)
- NaCl, 0.2 mol/l (overall active ingredients)
- dithiothreitol, 0.5 mmol/l (overall active ingredients)
- Triton X-100, 0.2% (v/v) (overall active ingredients)
- glycerol, 50% (v/v) (overall active ingredients)
- EDTA, 1 mmol/l (overall active ingredients)
- metal (overall material)
- Eco RI high concentration (overall active ingredients)
- Measurements
- overall: 2 7/8 in x 1 1/4 in; 7.3025 cm x 3.175 cm
- place made
- West Germany
- used
- United States: California, South San Francisco
- See more items in
- Medicine and Science: Biological Sciences
- Biotechnology and Genetics
- Science & Mathematics
- National Museum of American History
- Record ID
- nmah_1427287
- GUID (Link to Original Record)
- https://n2t.net/ark:/65665/ng49ca746ad-a807-704b-e053-15f76fa0b4fa
